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Target Identification, Validation and Screening​​

AnchorBio can take you from initial target identification and validation, all the way to hit identification and lead optimization. ​

Assay Design, Development and Validation

  • ​In vitro and cellular assays

  • ​Fit-for-purpose validation

  • ​Screen hundreds of compounds

  • ​Immuno-based assays​

  • Biochemical assays

  • ​Cell-based Assays

  • Surface Plasmon Resonance (SPR)

  • ​MS-based assays

Biomarker Discovery and Development

  • Mass Spectrometry-based Proteomics

    • Discovery

    • Targeted

    • Quantitative

    • Neoantigen discovery

    • Plasma/Serum, Cells, Tissues

    • Variant IDs

    • PTM

Screening Services

  • ​Cell-Based Assays

    • ​Cytokine production

    • ​Cell viability/proliferation assays

    • Apoptosis

    • Migration

    • Differentiation

    • Signaling pathways

    • Fluorescence-based assays

    • Reporter gene assays 

    • Neutrophil extracellular trap (NET) formation​

    • Cell morphology assays

    • Surface marker expression

  • ​ELISAs​

    • Commercially available​

    • ​Custom

  • ​Biochemical Assays

    • ​Drug target deconvolution

    • ​Protein-drug/protein-protein binding studies

    • ​Small molecule activity screening

  • ​Mass Spectrometry-Based Assays

    • ​Proteomic phenotypic screening

    • ​PISA assays (Chemo-proteomics)

    • ​Activity-based Protein Profiling (ABPP)​

    • Discovery

    • Targeted

    • Quantitative

    • Neoantigen discovery

    • Variant IDs

    • PTMs

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